![]() ![]() Blaschko lines follow embryotic cell migration patterns and are seen in some mosaic genetic disorders such as incontinentia pigmenti and pigment mosaicism. The linear arrangement of skin lesions in the Koebner phenomenon can be contrasted to both lines of Blaschko and dermatomal distributions. Warts and molluscum contagiosum are often listed as causing a Koebner reaction, but this is by direct inoculation of viral particles. Rarely Koebner phenomenon has been reported as a mechanism of acute myeloid leukemia dissemination. It is seen in: Ī similar response occurs in pyoderma gangrenosum and Behcet's syndrome, and is referred to as pathergy. The Koebner phenomenon describes skin lesions which appear at the site of injury. Causes of the Koebner phenomenon that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis (Darier disease). Toxicodendron dermatitis lesions are often linear from brushing up against the plant. Warts and molluscum contagiosum lesions can be spread in linear patterns by self-scratching (" auto-inoculation"). Conditions demonstrating linear lesions after a linear exposure to a causative agent include: molluscum contagiosum, warts and toxicodendron dermatitis (a dermatitis caused by a genus of plants including poison ivy). The Koebner phenomenon may result from either a linear exposure or irritation. The Koebner phenomenon or Köbner phenomenon ( UK: / ˈ k ɜː b n ər/, US: / ˈ k ɛ b-/), also called the Koebner response or the isomorphic response, attributed to Heinrich Köbner, is the appearance of skin lesions on lines of trauma. Appearance of skin lesions on lines of trauma Heinrich Köbner (1838–1904)
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